Xiaflex Injection
Non-Surgical Solution for Peyronie’s DiseaseXIAFLEX is medicine used to treat adult men with Peyronie’s disease who have a plaque that can be felt and a curve in their penis greater than 30 degrees when treatment is started. It is not known if XIAFLEX is safe and effective in children under the age of 18.
- Generic Name: Collagenase Clostridium Histolyticum
- Drug Strength: 0.9mg
- Pack Size: Per Vial
- FDA Approved
Xiaflex injection for Peyronie's Disease
Xiaflex is the brand name for collagenase clostridium histolyticum an enzyme injection that helps break down collagen buildup in the penile plaque responsible for curvature. This treatment is designed for men with stable Peyronie’s Disease where the curvature affects sexual performance.
At DOT Clinics Xiaflex injections are given by experienced urologists who specialize in male reproductive health procedures. This is an FDA-approved non-surgical treatment for Peyronie’s disease especially in moderate cases.
How Xiaflex Treatment Helps
Xiaflex injection for Peyronie’s disease works by:
- Breaking down the collagen in scar tissue
- Reducing curvature over time
- Improving sexual function
How Xiaflex Injection Works
Collagenase Injection MechanismAt DOT Clinics, we use Xiaflex injection as a safe, non-surgical treatment to target and break down hard scar tissue. This scar tissue is made of collagen, which can cause conditions like penile curvature or bent fingers. By softening this tissue, Xiaflex helps improve shape, flexibility, and overall function over time.
Step-by-Step Action-
Injection into the Scar Tissue
Our specialist carefully injects the medicine directly into the affected area, ensuring it works precisely where the problem exists. -
Breakdown of Collagen
The active ingredient, Collagenase Clostridium Histolyticum, begins breaking down the tough collagen fibers responsible for stiffness. -
Softening Over Time
As the collagen weakens, the tight and hardened tissue gradually becomes softer and more flexible. -
Gentle Stretching by Doctor
After the injection, the doctor may perform gentle stretching to help release the tightened tissue and enhance treatment results. -
Gradual Improvements
Over the following weeks, patients typically notice improved straightening, better movement, and enhanced comfort in daily life.
Benefits of Xiaflex Injection Treatment
Xiaflex therapy provides a modern, non-surgical way to manage Peyronie’s disease and offers several advantages compared to traditional surgery. It is designed to gradually improve penile curvature while keeping the procedure simple, safe, and comfortable for patients.
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Non-Surgical Approach
There is no need for major surgery or incisions. This means fewer risks, less discomfort, and a much shorter recovery time compared to surgical correction. -
Less Invasive
The treatment is performed through targeted injections only. It is a quick, clinic-based procedure that does not require hospital admission or general anesthesia. -
Improved Penile Curvature
Xiaflex works gradually over time by breaking down plaque inside the penis. With repeated sessions, many patients notice a visible reduction in curvature and improved straightness. -
Better Sexual Confidence
As curvature improves, many men feel more confident during sexual activity. This can help reduce stress and enhance overall quality of life. -
Outpatient Procedure
The entire treatment is completed on an outpatient basis, allowing patients to return home the same day without any hospital stay.
Consult Urology Specialist Today
Book an appointment with an experienced urology specialist at DOT Clinics Lahore & Multan for proper evaluation diagnosis and
customized treatment.
Xiaflex Injection Procedure Steps
the Xiaflex injection procedure is simple, quick, and done in a comfortable clinic setting. Our goal is to make the process smooth, safe, and easy to understand so you feel confident at every step.
We guide you through every step of the Xiaflex treatment process, ensuring you feel comfortable, informed, and supported throughout your journey.
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Step 1: Evaluation
Your doctor will carefully examine your condition. This may include a physical assessment and a discussion of your symptoms. Based on this evaluation, they will determine whether Xiaflex is the right treatment option for you. -
Step 2: Injection
The injection is administered directly into the plaque in Peyronie’s disease or the cord in Dupuytren’s contracture. The procedure is quick and typically causes only mild discomfort. -
Step 3: Observation
After the injection, you will be monitored for a short period to ensure there are no immediate side effects. Most patients can return home the same day. -
Step 4: Modeling
After 1–3 days, you will return to the clinic. The doctor will gently stretch or manipulate the treated area. This step helps break down the softened tissue and improves overall results. -
Step 5: Home Exercises
You may be advised to perform simple stretching exercises at home. These exercises support the treatment process and help improve flexibility and long-term outcomes.
Our team ensures that each step is carried out with care, helping you achieve the best possible results in a safe and comfortable environment.
How Many Xiaflex Injections are needed?
Treatment with Xiaflex is not the same for every patient. The number of injections depends on your condition, its severity, and how your body responds. For Peyronie’s Disease patients usually need about 2 to 4 treatment cycles with each cycle including 2 injections given a few days apart.
Recovery After Xiaflex Injection
Recovery after Xiaflex injection is usually smooth, and most patients are able to return to their normal daily routine quite quickly. There is no major downtime, but you do need to follow a few important instructions to ensure the best results and safe healing. After each injection, we advise you to take some care for a short period:
- You should avoid sexual activity for a short time after each injection so the tissue can heal properly.
- It is important that you follow all the instructions given by your doctor carefully.
- You should attend your follow-up sessions on time, as each session plays a role in improving results.
- If you notice any unusual swelling, pain, or discomfort, you should report it immediately to your doctor.
Important Safety Information
Always consult a qualified healthcare provider to determine if Xiaflex is right for you, consider all safety information and to ensure the treatment is performed safely.
- Do not use if the plaque involves the urethra.
- Avoid sexual activity for at least 4 weeks after the second injection of a cycle and until pain/swelling subsides.
- It is also normal to experience mild swelling, bruising, or slight discomfort in the treated area. In most cases, these symptoms are temporary and settle on their own without any treatment.
Side Effects
- Icthing or redness
- Swelling on the injected area
- Fliud buildup under skin
- Numbness or tingling
Expected Results of Xiaflex Treatment
The results of Xiaflex treatment can vary from person to person depending on the severity of Peyronie’s Disease and how your body responds to therapy. However, many patients do notice positive improvements over time.With proper treatment, you may experience:
- A noticeable reduction in penile curvature
- Improved ability to have comfortable sexual intercourse
- Better confidence and reduced emotional stress related to the condition
In some cases, more than one treatment cycle is needed to achieve the best possible outcome. We guide you step by step throughout the process so you know what to expect at each stage and can achieve safe improvement.
Xiaflex vs Surgery for Peyronie’s Disease
While surgery is an option for severe cases, Xiaflex offers a less invasive alternative.
| Feature | Xiaflex Injection | Surgery |
|---|---|---|
| Procedure Type | No surgical incision | More invasive with surgical incisions |
| Recovery Time | Short recovery time | Longer recovery period |
| Results | Gradual improvement over time | Immediate structural correction |
| Best For | Mild to moderate curvature | Typically used for severe deformities |
At DOT Clinics we help patients choose the most suitable option based on their condition.
Cost of Xiaflex Injection in Lahore & Multan
The cost of a Xiaflex collagenase clostridium histolyticum injection (0.9 mg) in Lahore and Multan, Pakistan, is approximately PKR 25,000 to PKR 30,000 per vial.
Understanding the cost of Xiaflex injection is important when planning your treatment. Below is a clear breakdown of what to expect:
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Treatment Cost
The listed price generally covers only the medication itself and does not include additional medical services. -
Additional Costs
Charges for the doctor’s consultation, examination, and injection procedure are usually billed separately. -
Consultation Fees
Specialist consultations (such as a urologist or sexologist) in Lahore typically range from PKR 1,000 to PKR 3,500. -
Treatment Scope
Treatment for Peyronie’s disease often requires multiple injections over a period of 4 to 6 months to achieve optimal results.
For an accurate cost estimate, it is always best to consult directly with your healthcare provider, as the total cost can vary depending on your condition and treatment plan.
Get details about your pricing and coverage options.
Why Choose Dot Clinics For Xiaflex Therapy?
Xiaflex treatment that helps break down scar tissue and restore natural shape with no downtime and safe clinically proven results. DOT Clinics is a trusted name in advanced urology and men’s health treatments offering expert care and personalized treatment plans.
- We only use 100% original Xiaflex injections thats why you receive genuine and approved treatment. This is very important because both safety and results depend on using the real product. Some other clinics may not offer authentic Xiaflex.
- Our team knows what they are doing with Xiaflex therapy. We follow the rules to make sure everything is safe and works well.
- We also understand that this is sensitive condition so your comfort and privacy are always our top priority. We make sure you feel comfortable at every stage of your treatment.
- We give you information about your treatment at every step. We tell you what to expect and how to get the best results. So you are never confused or insecure.
Common FAQs
Xiaflex helps reduce penile curvature in most patients and can improve sexual function over time. Results vary depending on the severity of the condition. Many patients notice gradual improvement after a few treatment cycles, especially when combined with proper doctor-guided care.
The cost of Xiaflex treatment in Pakistan typically ranges from PKR 150,000 to PKR 400,000 per treatment cycle. The final cost depends on the number of cycles required and the clinic’s expertise. Your doctor will explain the complete treatment plan before starting therapy.
Treatment usually takes a few weeks to a couple of months, depending on the number of cycles required. Each cycle is spaced to allow proper healing and response. Patients may start noticing gradual improvements within the first few weeks.
For many men, Xiaflex is preferred because it is non-surgical, has lower risks, and offers faster recovery. It allows treatment without incisions or hospital stay. However, the best option depends on your individual condition and should be decided by a specialist.
The procedure may cause mild discomfort, but local anesthesia is used to keep you comfortable during the injection. Most patients tolerate it well and feel only slight pressure.
Yes, Xiaflex therapy is available at DOT Clinics in Lahore and Multan. Experienced urology specialists provide complete care, from diagnosis to treatment and follow-up, ensuring patients receive proper guidance at every step.
Dr. Faisal Ilyas
Urologist & Peyronies Disease Expert
The content of this page is for informational purposes only.
Please consult with our Urologist & Endoscopic Surgeon for diagnosis and Peyronies Disease Treatment.




